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Oxford University Press, Journal of Pharmacy and Pharmacology, 7(53), p. 955-958, 2001

DOI: 10.1211/0022357011776379

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Studies on the reactivity of a tertiary allylic alcohol in an acetophenonic series, a model for natural products synthesis

Journal article published in 2001 by J. J. Hélesbeux ORCID, D. Séraphin, O. Duval, P. Richomme, J. Bruneton
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Abstract The synthesis of benzopyranic simplified analogues of dibenzopyranic natural compounds is described, together with the access to a precursor of a new furobenzopyranic natural product. These natural products have anti-cancer activity. The 1,3-diacetoxy-2-acetyl-4-(3-hydroxy-3-methylbut-1-enyl)benzene synthone is used as a common precursor to these structures.