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BioMed Central, Nutrition and Metabolism, 1(10), p. 9

DOI: 10.1186/1743-7075-10-9

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Dietary fortificant iron intake is negatively associated with quality of life in patients with mildly active inflammatory bowel disease

Journal article published in 2013 by Jonathan J. Powell, William B. Cook, Carol Hutchinson, Zoe Tolkien, Mark Chatfield, Dora Ia A. Pereira, Miranda Ce E. Lomer ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Abstract Background Iron deficiency anaemia and oral iron supplementation have been associated negatively with quality of life, and with adverse effects, respectively, in subjects with inflammatory bowel disease (IBD). Hence, the risk-benefit ratio of oral iron is not understood in this patient group. The present case–control study investigated whether dietary iron intake impacts on quality of life in IBD patients. Methods Quality of life, habitual dietary iron intakes and iron requirements were assessed in 29 patients with inactive or mildly active IBD as well as in 28 healthy control subjects. Results As expected, quality of life was worse in IBD patients as a whole in comparison to healthy controls according to EuroQol score and EuroQol VAS percentage (6.9 ± 1.6 vs 5.3 ± 0.6; p