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Thieme Gruppe, International Journal of Sports Medicine, 03(33), p. 218-223, 2012

DOI: 10.1055/s-0031-1291323

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Exercise Dose Response in Muscle

Journal article published in 2012 by Brian D. Duscha, Brian H. Annex, Johanna L. Johnson, Kim M. Huffman, Joseph A. Houmard, William E. Kraus ORCID
This paper is available in a repository.
This paper is available in a repository.

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Abstract

Exercise increases peak VO2 partially through muscle adaptations. However, understanding muscle adaptations related to exercise dose is incomplete. This study investigated exercise training dose on capillaries per fiber and capillaries per area; and citrate synthase from vastus lateralis and related both to changes in peak VO2. This randomized trial compared 3 exercise doses: low amount-moderate intensity (n = 40), low amount-high intensity (n=47 ), high amount-high intensity (n=41 ), and a control group (n=35). Both measures of capillary supply increased in all exercise groups (p