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Centers for Disease Control and Prevention, Emerging Infectious Diseases, 11(9), p. 1468-1470, 2003

DOI: 10.3201/eid0911.030349

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Flow Cytometry and T-Cell Response Monitoring after Smallpox Vaccination

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Data provided by SHERPA/RoMEO

Abstract

Orthopoxvirus zoonosis or smallpox as result of bioterrorism or biological warfare represents a risk for epidemic spread. By monitoring T-cell responses by flow cytometry, we observed a recall response after recent vaccination against smallpox. When the high similarity between the orthopoxviruses is considered, this rapid assay that uses vaccinia antigens could identify recently exposures.