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BioMed Central, Journal of Medical Case Reports, 1(1), 2007

DOI: 10.1186/1752-1947-1-101

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Pulmonary cystic disease in HIV positive individuals in the Democratic Republic of Congo: three case reports

Journal article published in 2007 by Steven Fj J. Callens ORCID, Faustin Kitetele, Patricia Lelo, Nicole Shabani, Jean Lusiama, Okitolanda Wemakoy, Robert Colebunders, Frieda Behets, van Annelies Rie, Annelies Van Rie ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Abstract Pulmonary emphysema and bronchiectasis in HIV seropositive patients has been described in the presence of injection drug use, malnutrition, repeated opportunistic infections, such as Pneumocytis jirovici pneumonia and Mycobacterium tuberculosis infection, and has been linked to the presence of HIV virus in lung tissue. Given the high burden of pulmonary infections and malnutrition among people living with HIV in resource poor settings, these individuals may be at increased risk of developing pulmonary emphysema, potentially reducing the long term benefit of antiretroviral therapy (ART) if initiated late in the course of HIV infection. In this report, we describe three HIV-infected individuals (one woman and two children) presenting with extensive pulmonary cystic disease.