Published in
Oxford University Press, International Journal of Epidemiology, 3(43), p. 878-886, 2014
DOI: 10.1093/ije/dyt267
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Leukocyte telomere length associates with prospective mortality independent of immune-related parameters and known genetic markers
Journal article published in 2014 by
Joris Deelen 
,
Marian Beekman,
Veryan Codd,
Stella Trompet,
Linda Broer ,
Sara Hägg,
S. Hagg,
Krista Fischer,
Peter E. Thijssen,
H. Eka D. Suchiman,
H. Eka D. Suchiman ,
Iris Postmus,
André G. Uitterlinden,
Albert Hofman,
Anton J. M. de Craen
and other authors.
,
Marian Beekman,
Veryan Codd,
Stella Trompet,
Linda Broer ,
Sara Hägg,
S. Hagg,
Krista Fischer,
Peter E. Thijssen,
H. Eka D. Suchiman,
H. Eka D. Suchiman ,
Iris Postmus,
André G. Uitterlinden,
Albert Hofman,
Anton J. M. de Craen
and other authors.
This paper is available in a repository.
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Abstract
Background: Human leukocyte telomere length (LTL) decreases with age and shorter LTL has previously been associated with increased prospective mortality. However, it is not clear whether LTL merely marks the health status of an individual by its association with parameters of immune function, for example, or whether telomere shortening also contributes causally to lifespan variation in humans.