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Elsevier, Schizophrenia Research, 1-3(120), p. 177-183, 2010

DOI: 10.1016/j.schres.2010.03.006

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Perinatal folate-related exposures and risk of psychotic symptoms in the ALSPAC birth cohort☆

Journal article published in 2010 by B. Glaser, Ae E. Ades, S. Lewis ORCID, P. Emmet, G. Lewis ORCID, G. Davey Smith, Gd Davey Smith, S. Zammit ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

It is unclear to what extent non-clinical psychotic experiences during childhood and adolescence share underlying aetiological mechanisms with schizophrenia. One candidate mechanism for schizophrenia involves the epigenetic status of the developing fetus, which depends on the internal folate-status of mother and child. Our study examines the relationships between multiple determinants of perinatal folate-status and development of psychotic experiences in adolescence.