Published in
BioMed Central, Malaria Journal, 1(10), 2011
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- [www.ncbi.nlm.nih.gov] | PDF
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Anaemia in a phase 2 study of a blood stage falciparum malaria vaccine
Journal article published in 2011 by
Guindo Aldiouma,
Ruth D. Ellis,
Michael P. Fay 
,
Alassane Dicko,
Miura Kazutoyo,
Issaka Sagara,
Merepen A. Guindo,
Merepen Aldiouma Guindo,
Mahamadou S. Sissoko,
Ogobara K. Doumbo,
Diallo Dapa
,
Alassane Dicko,
Miura Kazutoyo,
Issaka Sagara,
Merepen A. Guindo,
Merepen Aldiouma Guindo,
Mahamadou S. Sissoko,
Ogobara K. Doumbo,
Diallo Dapa
This paper is made freely available by the publisher.
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Abstract
Abstract Background A Phase 1-2b study of the blood stage malaria vaccine AMA1-C1/Alhydrogel was conducted in 336 children in Donéguébougou and Bancoumana, Mali. In the Phase 2 portion of the study (n = 300), no impact on parasite density or clinical malaria was seen; however, children who received the study vaccine had a higher frequency of anaemia (defined as haemoglobin