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CSIRO Publishing, Australian Journal of Chemistry, 11(59), p. 819
DOI: 10.1071/ch06324
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Preparation of the Central Tryptophan Moiety of the Celogentin/Moroidin Family of Anti-Mitotic Cyclic Peptides
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Abstract
The central functionalized tryptophan core of the celogentin/moroidin family of cyclic peptides has been prepared. The strategy incorporates a novel preparation of 4-iodobenzaldehyde and employs a Larock annulation as the key step.