Published in
The Royal Society, Journal of the Royal Society. Interface, suppl_1(7), 2009
DOI: 10.1098/rsif.2009.0177.focus
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Fluorescence two-dimensional difference gel electrophoresis for biomaterial applications
Journal article published in 2009 by
Laura E. McNamara,
Matthew J. Dalby,
Mathis O. Riehle 
,
Richard Burchmore
,
Richard Burchmore
This paper is made freely available by the publisher.
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Abstract
Fluorescence two-dimensional difference gel electrophoresis (DiGE) is rapidly becoming established as a powerful technique for the characterization of differences in protein expression levels between two or more conditions. In this review, we consider the application of DiGE—both minimal and saturation labelling—to biomaterials research, considering the challenges and rewards of this approach.