Published in

BioMed Central, Virology Journal, 1(10), 2013

DOI: 10.1186/1743-422x-10-82

Links

Tools

Export citation

Search in Google Scholar

Molecular typing of PPRV strains detected during an outbreak in sheep and goats in south-eastern Gabon in 2011

Journal article published in 2013 by Gael D. Maganga, Delphine Verrier, Rodrigo M. Zerbinati, R. Melim Zerbinati, Christian Drosten, Jan F. Drexler ORCID, Eric M. Leroy ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

Full text: Download

Green circle
Preprint: archiving allowed
Upload
Green circle
Postprint: archiving allowed
Upload
Green circle
Published version: archiving allowed
Upload
Policy details
Data provided by SHERPA/RoMEO

Abstract

Abstract Background Peste des petits ruminanats (PPR) is an economically important viral disease affecting goats and sheep. Four genetically distinct lineages of peste des petits ruminants virus (PPRV) have been identified. In Gabon, the virus has not so far been detected. Findings Epidemiological investigations of Aboumi PPR outbreak revealed a high case fatality rate in sheep (98.9%). We detected and characterized peste des petits ruminants virus (PPRV), in October 2011, during the suspected outbreak in sheep and goats in Aboumi village located in the south-eastern. PPRV RNA was detected in 10 of 14 samples from three sick animals. Phylogenetic analysis revealed that the PPRV strain belonged to lineage IV and was closely related to strain circulating in neighboring Cameroon. Conclusions This is the first molecular detection and typing of the PPRV strain associated with fatal PPR infection in these small ruminants and concrete evidence that PPRV is present and circulating in Gabon.