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BioMed Central, Virology Journal, 1(10), 2013

DOI: 10.1186/1743-422x-10-219

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Characterization of Farmington virus, a novel virus from birds that is distantly related to members of the family Rhabdoviridae

Journal article published in 2013 by Gustavo Palacios ORCID, Naomi L. Forrester, Nazir Savji, Amelia P. A. Travassos da Rosa, Hilda Guzman, Kelly DeToy, Vsevolod L. Popov, Peter J. Walker, W. Lipkin, Nikos Vasilakis, Robert B. Tesh
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Abstract Background Farmington virus (FARV) is a rhabdovirus that was isolated from a wild bird during an outbreak of epizootic eastern equine encephalitis on a pheasant farm in Connecticut, USA. Findings Analysis of the nearly complete genome sequence of the prototype CT AN 114 strain indicates that it encodes the five canonical rhabdovirus structural proteins (N, P, M, G and L) with alternative ORFs (> 180 nt) in the N and G genes. Phenotypic and genetic characterization of FARV has confirmed that it is a novel rhabdovirus and probably represents a new species within the family Rhabdoviridae. Conclusions In sum, our analysis indicates that FARV represents a new species within the family Rhabdoviridae.