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Association for Research in Vision and Ophthalmology, Investigative Ophthalmology & Visual Science, 9(53), p. 5806

DOI: 10.1167/iovs.12-10119

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Decline in DJ-1 and Decreased Nuclear Translocation of Nrf2 in Fuchs Endothelial Corneal Dystrophy

Journal article published in 2012 by Maya S. Bitar, Cailing Liu, Alireza Ziaei, Yuming Chen, Thore Schmedt, Ula V. Jurkunas ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Decreased levels of DJ-1 in FECD at baseline and under oxidative stress correlate with impaired Nrf2 nuclear translocation and heightened cell susceptibility to apoptosis.