Published in
Impact Journals, Aging, 9(6), p. 771-786, 2014
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Age- and glycemia-related miR-126-3p levels in plasma and endothelial cells
Journal article published in 2014 by
dummy-Author_name,
Fabiola Olivieri 
,
Massimiliano Bonafè,
Liana Spazzafumo,
Mirko Gobbi,
Francesco Prattichizzo ,
Rina Recchioni,
Fiorella Marcheselli,
Lucia La Sala,
Maria Rita Rippo,
Lucia La Sala,
Roberta Galeazzi,
Rippo Mr,
Gianluca Fulgenzi,
Sabrina Angelini
and other authors.
,
Massimiliano Bonafè,
Liana Spazzafumo,
Mirko Gobbi,
Francesco Prattichizzo ,
Rina Recchioni,
Fiorella Marcheselli,
Lucia La Sala,
Maria Rita Rippo,
Lucia La Sala,
Roberta Galeazzi,
Rippo Mr,
Gianluca Fulgenzi,
Sabrina Angelini
and other authors.
This paper is made freely available by the publisher.
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Abstract
Circulating miR-126-3p levels were determined in 136 healthy subjects (CTRs) aged 20-90 years and 193 patients with type-2 diabetes mellitus (T2DMs) aged 40-80 years, to explore the combined effect of age and glycemic state on miR-126-3p expression. Moreover, intra/extracellular miR-126-3p levels were measured in human endothelial cells (HUVECs) undergoing senescence under normo/hyper-glycemic conditions.