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Wiley, Angewandte Chemie International Edition, 51(50), p. 12299-12303, 2011

DOI: 10.1002/anie.201104104

Wiley, Angewandte Chemie, 51(123), p. 12507-12511, 2011

DOI: 10.1002/ange.201104104

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Ultrasmall rigid particles as multimodal probes for medical applications.

Journal article published in 2011 by François Lux, L. Vander Elst, Anna Mignot, Pierre Mowat, Cédric Louis, Sandrine Dufort, Claire Bernhard, Franck Denat, Frédéric Boschetti, Claire Brunet, Rodolphe Antoine ORCID, Philippe Dugourd, Sophie Laurent, Luce Vander Elst, Robert Muller and other authors.
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Abstract

Ultrasmall but multifunctional: Rigid imaging particles that are smaller than 5 nm in size can be obtained in a top-down process starting from a core-shell structure (core=gadolinium oxide; shell=polysiloxane). They represent the first multifunctional silica-based particles that are sufficiently small to escape hepatic clearance and enable animal imaging by four complementary techniques.