American Chemical Society, Journal of Medicinal Chemistry, 10(51), p. 2887-2890, 2008
DOI: 10.1021/jm8001444
Full text: Unavailable
5-HT1 receptor antagonists have been discovered with good selectivity over the 5-HT transporter. This is the first report of highly potent, selective ligands for the 5-HT1A/B/D receptors with low intrinsic activity, which represent a useful set of molecules for further understanding the roles of the 5-HT1 receptor subtypes and providing new approaches,for the treatment of depression.