Published in

Nature Research, Nature Reviews Molecular Cell Biology, 5(13), p. 328-335, 2012

DOI: 10.1038/nrm3335

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‘Intercellular communication: diverse structures for exchange of genetic information’

Journal article published in 2012 by Maria Mittelbrunn, Francisco Sánchez-Madrid ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

An emerging concept is that cellular communication in mammals can be mediated by the exchange of genetic information, mainly in the form of microRNAs. This can occur when extracellular vesicles, such as exosomes, secreted by a donor cell are taken up by an acceptor cell. Transfer of genetic material can also occur through intimate membrane contacts between donor and acceptor cells. Specialized cell-cell contacts, such as synapses, have the potential to combine these modes of genetic transfer.