Published in
American Society for Cell Biology, Molecular Biology of the Cell, 16(23), p. 3143-3155
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- [www.ncbi.nlm.nih.gov] | PDF
- [europepmc.org] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
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The CSC connects three major axonemal complexes involved in dynein regulation
Journal article published in 2012 by
Thomas Heuser 
,
Erin E. Dymek,
Jianfeng Lin,
Elizabeth F. Smith,
Daniela Nicastro
,
Erin E. Dymek,
Jianfeng Lin,
Elizabeth F. Smith,
Daniela Nicastro
This paper is made freely available by the publisher.
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Abstract
This study reveals the 3D structure of the CSC and its connections to three major axonemal complexes involved in dynein regulation, including the distal radial spoke and the nexin-DRC. The findings corroborate radial spoke heterogeneity and suggest a unique role for the distal spoke in calcium-mediated signal transduction and flagellar motility.