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American Society for Cell Biology, Molecular Biology of the Cell, 11(26), p. 2005-2019

DOI: 10.1091/mbc.e14-11-1561

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Centriolar satellite– and hMsd1/SSX2IP-dependent microtubule anchoring is critical for centriole assembly

Journal article published in 2015 by Akiko Hori, Christopher J. Peddie, Lucy M. Collinson ORCID, Takashi Toda
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Human Msd1/SSX2IP is a component of centriolar satellites and essential for microtubule anchoring to the centrosome. Anchoring defects lead to abnormal accumulation of centriolar components at centriolar satellites, which interferes with centriole assembly. Loss of Msd1/SSX2IP produces supernumerary centriole precursors specifically in tumor cells.