BioMed Central, Genome Medicine, 1(7), 2015
DOI: 10.1186/s13073-015-0182-y
Full text: Download
Abstract Genetic analyses of autoimmune diseases have revealed hundreds of disease-associated DNA variants, but the identity and function of the causal variants are understudied and warrant deeper mechanistic studies. Here, we highlight methods for deciphering how alleles that are associated with autoimmune disease alter the human immune system, and suggest strategies for future autoimmune genetic research.