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Springer Nature [academic journals on nature.com], Leukemia, 5(21), p. 1122-1124, 2007

DOI: 10.1038/sj.leu.2404617

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Are genotypes of glutathione S-transferase superfamily a risk factor for childhood acute lymphoblastic leukemia? Results of an Italian case–control study

Journal article published in 2007 by S. Pigullo, R. Haupt, C. Dufour, P. Di Michele, Mg G. Valsecchi, P. Dimichele, Vaksecchi Mg, G. Basso, C. Rizzari ORCID, A. Biondi, M. Lanciotti, M. Panciotti
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer accounting for approximately 25–30% of all childhood malignancies. Despite much investigation, the causes of the disease are not yet fully understood. Like many other cancers, ALL is considered to be a complex disease determined by a combination of genetic and environmental factors.