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Published in

BioMed Central, BMC Biology, 1(8), 2010

DOI: 10.1186/1741-7007-8-144

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How the vertebrates were made: selective pruning of a double-duplicated genome

Journal article published in 2010 by Gerard Manning ORCID, Eric Scheeff
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Abstract Vertebrates are the result of an ancient double duplication of the genome. A new study published in BMC Biology explores the selective retention of genes after this event, finding an extensive enrichment of signaling proteins and transcription factors. Analysis of their expression patterns, interactions and subsequent history reflect the forces that drove their evolution, and with it the evolution of vertebrate complexity. See research article: http://www.biomedcentral.com/1741-7007/8/146/abstract