International Classification of Primary Care in a cross-lingual terminology portal M. Jamoulle1, M. Pizzanelli2, J. Grosjean 3 , G. Kerdelhué 3, SJ. Darmoni 3&4 1 Department of General practice, Liege University, Belgium 2 Unidad docente asistencial rural de Florida, Uruguay 3 Deparment of Biomedical Informatics, Rouen University Hospital, Normandy & TIBS, LITIS EA 4108, France 4 LIMICS, INSERM, U1142, Paris, France. ICPC is available in the HeTOP cross-lingual terminology portal (URL: www.hetop.eu) [1] in 19 languages, mostly European (e.g. Spanish, Portuguese) but also in Japanese or Mandarin. The HeTOP interface has been also translated in 10 languages, including by Wonca colleagues (in Turkish, Vietnamese and Romanian). This is very important for non-English speakers to access a health Web site in his/her native language. Thanks to a partial manual mapping between ICPC2 and MeSH, it is now also possible to query PubMed from 20% of ICPC2 codes. This task is time consuming as in lot of cases, the mapping is 1 to N (one ICPC code generates several MeSH terms; e.g. the ICPC term "diverticular disease" is mapped to two MeSH terms " diverticulosis, colonic" and " diverticulitis". HeTOP currently contains 56 health terminologies and ontologies (only 17 are included in UMLS as most of them are French terminologies), 1,951,834 concepts, 6,636,000 terms, 8,023,181 relations and 1,340,855 relations. Overall, HeTOP contains 108 millions of SPARQL triplets. These figures underlines the possible application of the so called "health big data". Overall, the number of distinct UMLS concepts with at least one French translation in UMLS (MeSH, MedDRA, WHOART, ICPC) is 45,405 vs. 317,539 in HeTOP. 1. Grosjean, J; Merabti, T; Griffon, N; Dahamna, B & Darmoni, SJ. Teaching medicine with a terminology/ontology portal. Stud Health Technol Inform 2012:180;949-53. ; Peer reviewed