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American Society of Tropical Medicine and Hygiene, American Journal of Tropical Medicine and Hygiene, 6(92), p. 1137-1140, 2015

DOI: 10.4269/ajtmh.14-0211

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Dengue Seroprevalence in the French West Indies: A Prospective Study in Adult Blood Donors

Journal article published in 2015 by Maïna L'Azou, Janick Jean-Marie, Maël Bessaud, André Cabié ORCID, R. Cesaire, Raymond Césaire, Xavier de Lamballerie, Rémi Courbil, Pascale Richard
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Using an anti-dengue immunoglobulin G (IgG) indirect enzyme-linked immunosorbent assay, seroprevalence was determined among 783 adult blood donors in the French Caribbean islands of Guadeloupe and Martinique in 2011. Overall, 93.5% [91.5; 95.1] samples were positive for dengue antibodies, 90.7% (350 of 386) in Martinique and 96.2% (382 of 397) in Guadeloupe. Only 30% of these adults recalled having had dengue disease before. Serotype-specific neutralization assays applied to a subset of IgG-positive samples indicated that a majority (77 of 96; 80%) reacted to the four serotypes. These seroprevalence findings are the first reported for Guadeloupe and Martinique and are consistent with the dengue epidemiology in these territories.