Links

Tools

Export citation

Search in Google Scholar

Molecular approaches for eco-epidemiological studies of Paracoccidioides brasiliensis

Journal article published in 2009 by Richini-Pereira,Virgínia Bodelão, Sandra de Moraes Gimenes Bosco, Bosco,Sandra de Moraes Gimenes, Macoris,Severino Assis da Graça, Virgínia Bodelão Richini-Pereira, S. M. Gimenes Bosco ORCID, Sandra de Moraes Gimenes Bosco, Severino Assis da Graça Macoris, Raquel Cordeiro Theodoro ORCID, Theodoro,Raquel Cordeiro, Severino Assis da Graça Macoris, Eduardo Bagagli, Bagagli,Eduardo
This paper is available in a repository.
This paper is available in a repository.

Full text: Download

Question mark in circle
Preprint: policy unknown
Upload
Question mark in circle
Postprint: policy unknown
Upload
Question mark in circle
Published version: policy unknown
Upload

Abstract

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) ; Processo FAPESP: 06/03597-4 ; Processo FAPESP: 05/56771-9 ; Medical mycology has greatly benefited from the introduction of molecular techniques. New knowledge on molecular genetics has provided both theoretical and practical frameworks, permitting important advances in our understanding of several aspects of pathogenic fungi. Considering Paracoccidioides brasiliensis in particular, important eco-epidemiological aspects, such as environmental distribution and new hosts were clarified through molecular approaches. These methodologies also contributed to a better understanding about the genetic variability of this pathogen; thus, P. brasiliensis is now assumed to represent a species complex. The present review focuses on some recent findings about the current taxonomic status of P. brasiliensis, its phylogenetic and speciation processes, as well as on some practical applications for the molecular detection of this pathogen in environmental and clinical materials.