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Instituto Oswaldo Cruz, Ministério da Saúde, Memórias do Instituto Oswaldo Cruz., 7(103), p. 734-735, 2008

DOI: 10.1590/s0074-02762008000700018

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Enterotoxigenic and nontoxigenic Bacteroides fragilis strains isolated in Brazil

Journal article published in 2008 by Joaquim dos Santos-Filho, Geraldo R. de Paula, Ramos,Priscila Z., Ferreira,Eliane de O., Balassiano,Ilana T., Karla R. Miranda, Mariana F. Dias, Priscilla Ls S. Guimarães, Miranda,Karla R., Renata F. Boente, Dias,Mariana F., Heidi Pauer, Guimarães,Priscilla Ls, Priscila Z. Ramos, Boente,Renata F. and other authors.
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

The presence of enterotoxigenic Bacteroides fragilis and nontoxigenic B. fragilis (NTBF) among 109 strains isolated from 1980-2008 in Brazil were investigated by PCR. One strain, representing 0.9% of the total analyzed strains, harbored the bft gene which was identified as bft-1 isoform based on PCR-RFLP and sequencing. Forty-nine strains (44.9%) exhibited the NTBF pattern III which possesses the flanking region required for pathogenicity island acquisition in which the bft gene is codified. These data reinforce the potential of B. fragilis as an emerging enteropathogen in our country.