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Trajectories of cardiometabolic risk factors before diagnosis of three subtypes of type 2 diabetes: a post-hoc analysis of the longitudinal Whitehall II cohort study.
Journal article published in 2013 by
Kristine Færch 
,
Dr Witte ,
Ag Tabák,
Leigh Perreault,
Christian Herder,
Ej Brunner,
Mika Kivimäki ,
Dorte Vistisen
,
Dr Witte ,
Ag Tabák,
Leigh Perreault,
Christian Herder,
Ej Brunner,
Mika Kivimäki ,
Dorte Vistisen
Abstract
Most clinicians acknowledge that type 2 diabetes is multifactorial and has heterogeneous characteristics, but neither prevention nor treatment is systematically stratified. To address the heterogeneity of the disease, we examined whether patients diagnosed on the basis of fasting glucose concentrations, those diagnosed on the basis of 2 h concentrations, and those diagnosed on the basis of both criteria differed in terms of pathogenesis or cardiovascular risks.