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BMJ Publishing Group, Annals of the Rheumatic Diseases, 6(62), p. 568-571

DOI: 10.1136/ard.62.6.568



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In vitro growth rate of fibroblast-like synovial cells is reduced by methotrexate treatment

Journal article published in 2003 by I. Derese, F. P. Luyten, R. J. U. Lories ORCID, C. De Bari
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Objective: To study FLS cultures, with particular attention to differences in growth rate of FLS from patients with rheumatoid arthritis (RA) and from other arthritic patients. Additionally, to analyse the influence of methotrexate (MTX) treatment, patient age, and disease duration on FLS growth characteristics.