Published in
Public Library of Science, PLoS ONE, 9(8), p. e74220, 2013
DOI: 10.1371/journal.pone.0074220
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- [www.ncbi.nlm.nih.gov] | PDF
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Effects of ascent to high altitude on human antimycobacterial immunity.
Journal article published in 2013 by
Sarah Eisen,
Louise Pealing,
Rw Aldridge,
Mj Siedner 
,
Alejandro Necochea,
Inna Leybell,
Teresa Valencia,
Beatriz Herrera,
Siouxsie Wiles,
Js Friedland,
Rh Gilman,
Ca Evans
,
Alejandro Necochea,
Inna Leybell,
Teresa Valencia,
Beatriz Herrera,
Siouxsie Wiles,
Js Friedland,
Rh Gilman,
Ca Evans
This paper is made freely available by the publisher.
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Abstract
Tuberculosis infection, disease and mortality are all less common at high than low altitude and ascent to high altitude was historically recommended for treatment. The immunological and mycobacterial mechanisms underlying the association between altitude and tuberculosis are unclear. We studied the effects of altitude on mycobacteria and antimycobacterial immunity.