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Oxford University Press, The American Journal of Clinical Nutrition, 3(101), p. 440-448, 2015

DOI: 10.3945/ajcn.114.096750

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Is complying with the recommendations of sodium intake beneficial for health in individuals at high cardiovascular risk? Findings from the PREDIMED study

Journal article published in 2014 by Jordi Merino, Marta Guasch-Ferre ORCID, Miguel A. Martinez-Gonzalez, Dolores Corella, Ramon Estruch, Montserrat Fito ORCID, Emilio Ros, Fernando Aros, E. Gomez-Gracia, Mónica Bullo, Manuel Monino, Enrique Gómez-Gracia, José Lapetra, Lluís Serra-Majem, Cristina Razquin and other authors.
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

Is complying with the recommendations of sodium intake beneficial for health in individuals at high cardiovascular risk? Findings from the PREDIMED study ; Background: Excess sodium intake is associated with high blood pressure, a major risk factor for cardiovascular disease (CVD). It is unknown whether decreasing sodium intake to 2300 to ≤3400 mg/d), or very high (>3400 mg/d). Subsequently, 1-y and 3-y changes in sodium intake were calculated. Multivariate relative risks were assessed by using Cox proportional hazards ratios. Marginal structural models with inverse probability weighting were used to test the effect of changes in sodium intake and the Mediterranean diet (MedDiet). Results: We documented 125 CVD events and 131 deaths after a 4.8-y median follow-up. Sodium intake