Accumulation of atmospheric CO₂ is increasing the temperature and concentration of CO₂ in near-shore marine systems. These changes are occurring concurrently with increasing alterations to local conditions, including nutrient pollution and exploitation of selected biota. While the body of evidence for the negative effects of climate change is rapidly increasing, there is still only limited recognition that it may combine with local stressors to accelerate degradation. By recognizing such synergies, however, it may be possible to actively manage and improve local conditions to ameliorate the effects of climate change in the medium-term (e.g., by reducing nutrient pollution or restoring populations of herbivores). Ultimately, however, the most effective way to increase the sustainability of near-shore marine systems into the future will be to decrease our reliance on carbon-based sources of energy to reduce the negative effects of climate change. ; http://www.mdpi.com/2071-1050/2/8/2593/ ; Laura J. Falkenberg, Owen W. Burnell, Sean D. Connell and Bayden D. Russell