Dissemin is shutting down on January 1st, 2025

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Taylor and Francis Group, OncoImmunology, 8(1), p. 1420-1421

DOI: 10.4161/onci.21120

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Tumor-infiltrating lymphocytes and outcome in Merkel cell carcinoma, a virus-associated cancer

Journal article published in 2012 by Harri Sihto ORCID, Heikki Joensuu
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

An intense immune infiltrate, enriched in T cells, is associated with the presence of Merkel cell polyomavirus (MCPyV) DNA in Merkel cell carcinoma (MCC), a rare skin cancer. High tumor-infiltrating T-cell counts are associated with favorable survival regardless of the tumor MCPyV status. Hence, boosting host immune functions might constitute a new approach for the treatment of MCC.