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The Royal Society, Interface Focus, 1(4), p. 20130040-20130040
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Carbonate hydroxyapatite functionalization: a comparative study towards (bio)molecules fixation
Journal article published in 2013 by
Laura Russo 
,
Francesca Taraballi,
Cristina Lupo,
Ana Poveda ,
Jesús Jiménez-Barbero ,
Monica Sandri,
Anna Tampieri,
Francesco Nicotra,
Laura Cipolla
,
Francesca Taraballi,
Cristina Lupo,
Ana Poveda ,
Jesús Jiménez-Barbero ,
Monica Sandri,
Anna Tampieri,
Francesco Nicotra,
Laura Cipolla
This paper is made freely available by the publisher.
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Abstract
Different methods for the functionalization of carbonate hydroxyapatite granules with free amine groups by reaction with (3-aminopropyl)triethoxysilane (APTES) have been compared in order to improve the potential for tethering of bioactive molecules to bioceramics. The combined use of tetraethoxyorthosilicate and APTES with acid catalysis resulted in an evident increase in amine surface grafting.