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Wiley, Chirality, 10(26), p. 640-650, 2014

DOI: 10.1002/chir.22355

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Synthesis, Enzymatic Resolution, and Stereochemical Characterization of Isoparaconic Acid Derivatives: A Combined Experimental and Theoretical Investigation

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Enantiomerically enriched isoparaconic acid derivatives were obtained by kinetic enzymatic resolution. To explain the solvent dependence observed for their optical rotatory power a computational investigation of their chiroptical properties was performed