Published in
Springer, Journal of Endocrinological Investigation, 2(39), p. 207-213, 2015
DOI: 10.1007/s40618-015-0333-4
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d-Aspartic acid stimulates steroidogenesis through the delay of LH receptor internalization in a mammalian Leydig cell line
Journal article published in 2015 by
A. Di Nisio,
L. De Toni,
M. Ferigo,
M. S. Rocca 
,
E. Speltra,
A. Ferlin ,
C. Foresta
,
E. Speltra,
A. Ferlin ,
C. Foresta
This paper is made freely available by the publisher.
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Abstract
Recent experimental evidence on non-mammalian animal models showed that D-Aspartic acid (d-Asp) administration increases testosterone levels through upregulation of StAR in Leydig cells. In this study, we aimed to investigate in vitro the signaling pathway associated with d-Asp stimulation in MA-10 murine Leydig cells.