Published in
American Thoracic Society, American Journal of Respiratory and Critical Care Medicine, 4(182), p. 489-500, 2010
DOI: 10.1164/rccm.200906-0925oc
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- American Thoracic Society
- [www.ncbi.nlm.nih.gov] | PDF
- [europepmc.org] | PDF
- [www.researchgate.net] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
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Activating Transcription Factor 3 Confers Protection against Ventilator-induced Lung Injury
Journal article published in 2010 by
Ali Akram,
Bing Han,
Hussain Masoom,
Claudia Peng,
Emily Lam,
Michael L. Litvack,
Michael L. Litvack,
Xiaohui Bai,
Yuexin Shan 
,
Tsonwin Hai,
Jane Batt,
Arthur S. Slutsky,
Haibo Zhang,
Wolfgang M. Kuebler,
Jack J. Haitsma
and other authors.
,
Tsonwin Hai,
Jane Batt,
Arthur S. Slutsky,
Haibo Zhang,
Wolfgang M. Kuebler,
Jack J. Haitsma
and other authors.
This paper is available in a repository.
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Abstract
Rationale: Ventilator-induced lung injury (VILI) significantly contributes to mortality in patients with acute respiratory distress syndrome, the most severe form of acute lung injury. Understanding the molecular basis for response to cyclic stretch (CS) and its derangement during high-volume ventilation is of high priority.