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American Society for Microbiology, Antimicrobial Agents and Chemotherapy, 5(49), p. 2122-2125, 2005

DOI: 10.1128/aac.49.5.2122-2125.2005

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Nationwide Study of Escherichia coli and Klebsiella pneumoniae Producing Extended-Spectrum β-Lactamases in Spain

Journal article published in 2005 by J. R. Hernández, L. Martínez-Martínez, R. Cantón, T. M. Coque, A. Pascual ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

ABSTRACT Clonal dissemination of extended-spectrum β-lactamases (ESBL) in 170 Escherichia coli isolates and 70 Klebsiella pneumoniae isolates from a nationwide study of 40 Spanish centers in 2000 was not observed in most centers. The most prevalent ESBL were CTX-M-9 (27.3%), SHV-12 (23.9%), and CTX-M-14 (20.5%) for E. coli and TEM-3 (16.7%) and TEM-4 (25%) for K. pneumoniae . A new ESBL, TEM-133, with mutations L21F, E104K, and R164S, was identified.