Published in
American Society of Hematology, Blood, 19(127), p. 2298-2309, 2016
DOI: 10.1182/blood-2015-08-664631
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- American Society of Hematology | PDF
- [europepmc.org] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
- [www.repository.cam.ac.uk] | PDF
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Analysis of Jak2 signaling reveals resistance of mouse embryonic hematopoietic stem cells to myeloproliferative disease mutation
Journal article published in 2016 by
Maria I. Mascarenhas,
Wendi A. Bacon 
,
Chrysa Kapeni,
Simon R. Fitch,
Gillian Kimber,
S. W. Priscilla Cheng,
Juan Li,
Anthony R. Green,
Katrin Ottersbach
,
Chrysa Kapeni,
Simon R. Fitch,
Gillian Kimber,
S. W. Priscilla Cheng,
Juan Li,
Anthony R. Green,
Katrin Ottersbach
This paper is made freely available by the publisher.
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Abstract
Key Points Emerging HSCs require Jak2 and Pi3k signaling for proliferation and survival. Embryonic HSCs are unaffected by the JAK2V617F mutation.