Published in
American Thoracic Society, American Journal of Respiratory and Critical Care Medicine, 4(193), p. 417-426, 2016
DOI: 10.1164/rccm.201508-1562oc
Links
- ORCID
- American Thoracic Society
- ORCID
- [www.ncbi.nlm.nih.gov] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
- [europepmc.org] | PDF
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Cystic Fibrosis Transmembrane Conductance Regulator in Sarcoplasmic Reticulum of Airway Smooth Muscle. Implications for Airway Contractility
Journal article published in 2016 by
Daniel P. Cook 
,
Michael V. Rector,
Drake C. Bouzek,
Andrew S. Michalski,
Nicholas D. Gansemer,
Leah R. Reznikov ,
Xiaopeng Li,
Mallory R. Stroik,
Lynda S. Ostedgaard,
Mahmoud H. Abou Alaiwa,
Michael A. Thompson,
Y. S. Prakash,
Ramaswamy Krishnan,
David K. Meyerholz,
Chun Y. Seow
and other authors.
,
Michael V. Rector,
Drake C. Bouzek,
Andrew S. Michalski,
Nicholas D. Gansemer,
Leah R. Reznikov ,
Xiaopeng Li,
Mallory R. Stroik,
Lynda S. Ostedgaard,
Mahmoud H. Abou Alaiwa,
Michael A. Thompson,
Y. S. Prakash,
Ramaswamy Krishnan,
David K. Meyerholz,
Chun Y. Seow
and other authors.
This paper is available in a repository.
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Abstract
Rationale: An asthma-like airway phenotype has been described in people with cystic fibrosis (CF). Whether these findings are directly caused by loss of CF transmembrane conductance regulator (CFTR) function or secondary to chronic airway infection and/or inflammation has been difficult to determine.