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American Society for Microbiology, Antimicrobial Agents and Chemotherapy, 1(60), p. 682-685, 2016

DOI: 10.1128/aac.02234-15

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Azole Resistance in Aspergillus fumigatus Clinical Isolates from an Italian Culture Collection

Journal article published in 2015 by Cristina Lazzarini, Maria Carmela Esposto, Anna Prigitano, Massimo Cogliati, Gabriella De Lorenzis ORCID, Anna Maria Tortorano
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

ABSTRACT The aims of the study were to investigate the prevalence of azole resistance among Aspergillus fumigatus clinical isolates. A total of 533 clinical isolates that had been collected between 1995 and 2006, from 441 patients, were screened. No resistance was detected in isolates collected between 1995 and 1997. Starting in 1998, the resistance rate was 6.9%; a total of 24 patients (6.25%) harbored a resistant isolate. The TR34/L98H substitution was found in 21 of 30 tested isolates.