Published in
American Association for the Advancement of Science, Science Translational Medicine, 325(8), 2016
DOI: 10.1126/scitranslmed.aad2355
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Aurora kinase inhibitor nanoparticles target tumors with favorable therapeutic index in vivo
Journal article published in 2016 by
Susan Ashton,
Young Ho Song,
Jim Nolan,
Elaine Cadogan,
Jim Murray,
Rajesh Odedra,
John Foster,
Peter A. Hall,
Susan Low,
Paula Taylor,
Rebecca Ellston,
Urszula M. Polanska,
Joanne Wilson,
Colin Howes,
Aaron Smith 
and other authors.
and other authors.
This paper is available in a repository.
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Abstract
A nanoparticle formulation of an Aurora B kinase inhibitor uses ion pairing to achieve controlled release and efficacious, nontoxic target inhibition in tumors.