Published in
American Society for Microbiology, Antimicrobial Agents and Chemotherapy, 11(53), p. 4903-4906, 2009
DOI: 10.1128/aac.00640-09
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- [www.researchgate.net] | PDF
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- [www.ncbi.nlm.nih.gov] | PDF
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In Vitro Activities of Trioxaquines against Schistosoma mansoni
Journal article published in 2009 by
Jérôme Boissier 
,
Frédéric Coslédan,
Anne Robert,
Bernard Meunier
,
Frédéric Coslédan,
Anne Robert,
Bernard Meunier
This paper is made freely available by the publisher.
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Abstract
ABSTRACT We report the in vitro activities of trioxaquines against larval and adult-stage schistosomes at 5 and 50 μg/ml, respectively. Such activities are equivalent to that of praziquantel, the major and rather unique drug currently used for the treatment of schistosomiasis. In this range of concentrations, artemisinin derivatives (artesunate and artemether) have no activity.