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Elsevier, Microelectronic Engineering, (124), p. 13-16

DOI: 10.1016/j.mee.2014.04.016

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Optimized fabrication protocols of microfluidic devices for X-ray analysis

Journal article published in 2014 by Rossella Catalano, Gerardo Perozziello, Giuseppina Simone, Patrizio Candeloro, Francesco T. Gentile ORCID, Maria Laura Coluccio ORCID, Francesca Pardeo, Manfred C. Burghammer, Giovanni Cuda, Christian Riekel, Enzo M. Di Fabrizio
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

Microfluidics combined with X-ray scattering techniques allows probing conformational changes or assembly processes of biological materials. Our aim was to develop a highly X-ray transparent microfluidic cell for detecting small variations of X-ray scattering involved in such processes. We describe the fabrication of a polyimide microfluidic device based on a simple, reliable and inexpensive lamination process. The implemented microstructured features result in windows with optimized X-ray transmission. The microfluidic device was characterized by X-ray microbeam scattering at the ID13 beamline of the European Synchrotron Radiation Facility. © 2014 Elsevier B.V. All rights reserved.