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Bentham Science Publishers, Mini-Reviews in Medicinal Chemistry, 6(6), p. 727-737

DOI: 10.2174/138955706777435733

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HIV-1 RNase H: Recent Progress in an Exciting, yet Little Explored, Drug Target

Journal article published in 2006 by Enzo Tramontano ORCID
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

Full text: Unavailable

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Abstract

HIV-1 reverse transcriptase-associated ribonuclease H (RNase H) is an attractive non traditional target for drug development which has been, so far, little explored. All drugs shown to inhibit HIV-1 RNase H are reported, including the recently described classes of compounds that interact with the metal ions in the active site.