Bentham Science Publishers, Mini-Reviews in Medicinal Chemistry, 6(6), p. 727-737
DOI: 10.2174/138955706777435733
Full text: Unavailable
HIV-1 reverse transcriptase-associated ribonuclease H (RNase H) is an attractive non traditional target for drug development which has been, so far, little explored. All drugs shown to inhibit HIV-1 RNase H are reported, including the recently described classes of compounds that interact with the metal ions in the active site.