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Wiley, Movement Disorders, 9(27), p. 1182-1185, 2012

DOI: 10.1002/mds.25102

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Is Transcranial Sonography Useful to Distinguish Scans Without Evidence of Dopaminergic Deficit Patients From Parkinson's Disease?

Journal article published in 2012 by Heike Stockner, Petra Schwingenschuh, Atbin Djamshidian, Laura Silveira-Moriyama, Petra Katschnig, Klaus Seppi, John Dickson, Mark J. Edwards ORCID, Andrew J. Lees, Werner Poewe, Kailash P. Bhatia ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Approximately 10% of patients clinically diagnosed with early Parkinson's disease (PD) subsequently have normal dopaminergic functional imaging. Transcranial sonography (TCS) has been shown to detect midbrain hyperechogenicity in approximately 90% of Parkinson's disease (PD) patients and 10% of the healthy population. The aim of this study was to investigate the prevalence of midbrain hyperechogenicity in patients with suspected parkinsonism and scans without evidence of dopaminergic deficit (SWEDD), in comparison to PD patients.