Published in
American Society of Hematology, Blood, 11(126), p. 1336-1345, 2015
DOI: 10.1182/blood-2015-02-626291
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L-selectin controls trafficking of chronic lymphocytic leukemia cells in lymph node high endothelial venules in vivo
Journal article published in 2015 by
Fanny Lafouresse,
Elisabeth Bellard,
Camille Laurent 
,
Christine Moussion,
Jean-Jacques Fournie,
Loïc Ysebaert,
Jean-Philippe Girard
,
Christine Moussion,
Jean-Jacques Fournie,
Loïc Ysebaert,
Jean-Philippe Girard
This paper is made freely available by the publisher.
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Abstract
Key Points In vivo imaging reveals that CLL cells bind to lymph node high endothelial venules via an L-selectin–dependent multistep adhesion cascade. Interference with L-selectin–mediated trafficking in high endothelial venules could limit dissemination of CLL cells to lymph nodes.