Men's health has become so important that it is now virtually a political issue. With advancing age, testosterone levels decrease and this has an effect on body composition, mood, and sexual function. There have been many attempts to counteract what has now become known as the 'andropause'. Many questions need to be answered. For example, does the serum testosterone level need to be restored to normal? Is it always abnormal in older men? Will this restoration to normal levels enhance well being without incurring other risks? Are gels more effective than patches? Not all of these questions can be answered in a single paper, but some of them are. However, the big question remains: will men's health continue to be of major importance, and will testosterone replacement be generally accepted?