HIV-infected individuals with the CCR5Δ32/CCR5 genotype have lower HIV RNA levels and higher CD4 cell counts in the early years of the infection than do patients with the wild type
Journal article published in 1997 by
Tl Katzenstein 
,
Jesper Eugen-Olsen ,
Bo Hofmann,
Thomas Benfield,
Court Pedersen,
Akn Iversen,
Am Sørensen,
Peter Garred,
Uffe Koppelhus,
Arne Svejgaard,
Jan Gerstoft
,
Jesper Eugen-Olsen ,
Bo Hofmann,
Thomas Benfield,
Court Pedersen,
Akn Iversen,
Am Sørensen,
Peter Garred,
Uffe Koppelhus,
Arne Svejgaard,
Jan Gerstoft
Abstract
The relations among serum HIV RNA levels, CD4 cell counts, presence of the mutant CCR5-allele in heterozygous form, and clinical outcome was analyzed in 96 patients from the Copenhagen AIDS Cohort. In the early years of the infection, patients with the CCR5Δ32/CCR5 genotype had significantly lower HIV RNA levels (p = 0.005) and higher CD4 cell counts (p