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American Society for Microbiology, Journal of Clinical Microbiology, 12(43), p. 6176-6182, 2005

DOI: 10.1128/jcm.43.12.6176-6182.2005

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Molecular Identification of Adenoviruses in Clinical Samples by Analyzing a Partial Hexon Genomic Region†

Journal article published in 2005 by I. Casas, A. Avellon ORCID, M. Mosquera, O. Jabado, J. E. Echevarria, R. H. Campos, M. Rewers, P. Perez-Breña, W. I. Lipkin, G. Palacios ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

ABSTRACT Here we present a system for adenovirus detection and genotyping based on PCR amplification and phylogenetic analysis of a conserved hexon gene fragment. The system was validated using 157 sequences (86 previously typed and 71 clinical samples) and correctly identified species and serotype in 100% and 84% of sequences, respectively. Known associations between specific serotypes and clinical syndromes are verified. Possible new associations are described to allow further independent testing.