American Society for Microbiology, Journal of Clinical Microbiology, 12(43), p. 6183-6185, 2005
DOI: 10.1128/jcm.43.12.6183-6185.2005
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ABSTRACT The association between human immunodeficiency virus (HIV) DNA load and immunologic parameters was investigated in 163 HIV-infected patients with undetectable plasma viremia during highly active antiretroviral therapy (HAART). Patients with HIV DNA below the 25th percentile (133 copies/10 6 peripheral blood mononuclear cells) had higher pre-HAART ( P = 0.001) and current ( P = 0.005) CD4 counts and a prolonged duration of treatment ( P = 0.001). At adjusted analysis, prolonged duration of treatment was independently associated with lower ( P = 0.006) and undetectable ( P < 0.001) HIV DNA values.